Founded in 1948, Desert Regional Medical Center is a 387-bed tertiary acute care hospital located in Palm Springs. The emergency department is the Coachella Valley's only designated trauma center, serving more than 8,000 square miles of Southeastern California.

Desert Regional Medical Center offers a comprehensive array of services that includes: Emergency/Trauma Services, Comprehensive Cancer Center, Institute of Clinical Orthopedics and Neurosciences, Bariatric Specialists, Joslin Diabetes Center, El Mirador Imaging Center and inpatient and outpatient rehabilitation services. In addition, Desert Regional has expanded three of its clinics to the La Quinta Medical Center at 47647 Caleo Bay: Comprehensive Cancer Center, Institute of Clinical Orthopedics and Neurosciences, and La Quinta Imaging.

Desert Regional Medical Center has received The Joint Commission's Gold Seal of Approval, its highest level of certification, for their Advanced Primary Stroke Center and Advanced Congestive Heart Failure program.